First Case of Red Meat Allergy Caused by Tick Bite Reported in Serbia

Dr. Pavle Banović, from the Faculty of Medicine in Novi Sad and the Pasteur Institute, explained the condition in detail for the association’s website, noting that not all causes of the allergy are fully understood.

"Alpha-gal syndrome is a collection of symptoms linked to an allergy to a specific carbohydrate called galactose-alpha-1,3-galactose, commonly referred to as alpha-gal," said Dr. Banović.

"Although the precise mechanisms that lead to the development of this allergy are still being studied, numerous scientific findings have confirmed a strong link between frequent tick bites and the onset of the syndrome, as ticks carry the alpha-gal molecule."

Dr. Banović also described the variety of reactions individuals with this condition may experience.

"Symptoms can range from mild skin irritation to severe anaphylactic reactions. For some, the trigger may be a tick or mosquito bite, while for others, consuming red meat, especially organ meats, can provoke issues such as abdominal pain, rashes, or even anaphylaxis," he explained.

One of the unique characteristics of alpha-gal syndrome, according to Dr. Banović, is the delayed onset of symptoms, which can appear several hours after exposure.

"Unlike many food allergies, reactions in alpha-gal syndrome are often delayed, which makes it difficult for patients to associate their symptoms with a specific food," he noted.

"That’s why the term ‘red meat allergy’ is helpful; it's a clear and relatable way to explain to patients and their families what needs to be avoided in their diet."

This marks an important step in raising awareness of a little-known condition that may become increasingly relevant as tick populations expand due to climate and environmental changes.